During the development of new vaccine of covid-19, there was a lot of discussion about M-RNA (Messenger Ribonucleic Acid) technology this year. It is more effective than conventional vaccines, and can be developed and produced at a lower cost. mRNA is a single-stranded molecule that contains information from DNA. This vaccine provides the genetic code to the cells, from which they release proteins. With this protein, immunity (immune response) starts developing in the body. Experts believe that m-RNA based vaccine can also be developed for incurable diseases like cancer.
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1. Precision Medicine
Presently it is being used effectively in oncology. In future, it can be used in the treatment of rare and genetic diseases. It is also an effective method in dealing with infectious diseases. Rather, it addresses individual challenges related to a patient’s genetics, environment, and lifestyle. Based on the information related to the patient’s genome, the doctor can recommend therapy or drugs to him. This makes the treatment more likely to be effective. However, mainstreaming precision medicine into the healthcare system may take time.
2. New method of reducing LDL
High levels of cholesterol in the blood, especially low-density lipoprotein (LDL-C), is a major cause of heart disease. Researchers have done a lot of work over the years to find out the effect of inclisiran in the treatment of early hyperlipidemia (uncontrolled concentration of fats or lipids in the blood). It is a blood soluble RNA based medicine, which targets the PCSK9 protein. Its use results in an effective and sustained reduction in LDL-C. After the approval of Inclisiran in the US, this drug has raised hopes of better treatment of heart patients.
3. New drug for diabetes type-2 treatment
Diabetes is becoming a serious health problem in India. There are a number of drugs already available to lower blood sugar, but the newly developed drug only needs to be taken once a week. Supplementation with glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide receptor agonists (GLP-1) causes the pancreas to release insulin and inhibit the hormone glucagon, thereby controlling postprandial blood sugar spikes. Also, it slows down the process of digestion. It lowers hemoglobin A1C in type-2 diabetes and is also helpful in weight loss. This has raised hopes that this drug may be effective in preventing diabetes and obesity.
After the corona virus epidemic, the demand for telemedicine and telehealth has increased significantly. With the help of internet, doctors sitting somewhere far away have started providing clinical and non-clinical services. There is a hope of getting better treatment for the people living in remote areas of the country. Smart medical devices and wearables can bring revolutionary changes in this direction. Several manufacturers are developing new types of devices that capture health information remotely. Due to this, in the coming time, through wearables, information about heart rate or blood oxygen can be sent and treatment can be done by sending it to a doctor sitting far away.